The purpose of this study is to assess the role of the pathogeni city of odontogenic infection in the development of CVD. The objects of the study were 64 patients, of which 31 patients were included in group 1 at the stages of treatment for CVD, in which the pathogen "(Porphyromonasgingivalis) was detected by microbiological examination. Group 2 (34) patients were patients with CVD without periodontal pathology. Microbiological, immunological and enzyme immunoassay methods were used. Revealed a high prevalence of gingivitis, respectively, in patients with CVD. A decrease in the synthesis of a chemotactic factor in patients with CVD is accompanied by a significant decrease in the content of IL-8 in mixed saliva, which leads to a reduction in the life span of neutrophils.
periodontitis, CVD, pathogenic microflora, chemotaxis, IL-8
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